×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
CLINGEN
Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation.
11406561
2001
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
CLINGEN
Brca1 controls homology-directed DNA repair.
10549283
1999
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
CLINGEN
Growth retardation and tumour inhibition by BRCA1.
8589721
1996
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
CLINGEN
Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression.
7795653
1995
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
CLINGEN
High allele loss rates at 17q12-q21 in breast and ovarian tumors from BRCAl-linked families. The Breast Cancer Linkage Consortium.
7669740
1995
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
CLINGEN
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells.
9774970
1998
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
CLINGEN
Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells.
10198641
1999
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
CLINGEN
Gamma-rays-induced death of human cells carrying mutations of BRCA1 or BRCA2.
10602489
1999
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
CLINGEN
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.
7545954
1994
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
CLINGEN
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
15829967
2005
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
GENOMICS_ENGLAND
Consensus for genes to be included on cancer panel tests offered by UK genetics services: guidelines of the UK Cancer Genetics Group.
29661970
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
GENOMICS_ENGLAND
Neuronal migration defect in a BRCA1 gene carrier: possible focal nullisomy?
12624153
2003
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
GeneticVariation
UNIPROT
Twenty-three novel BRCA1 and BRCA2 sequence alterations in breast and/or ovarian cancer families in Southern Germany.
12938098
2003
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
GeneticVariation
UNIPROT
BRCA1 R841W: a strong candidate for a common mutation with moderate phenotype.
8968716
1996
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
GeneticVariation
UNIPROT
Novel germline mutations in the BRCA1 and BRCA2 genes in Indian breast and breast-ovarian cancer families.
14722926
2004
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
GeneticVariation
UNIPROT
Suggestion of BRCA1 c.5339T>C (p.L1780P) variant confer from 'unknown significance' to 'Likely pathogenic' based on clinical evidence in Korea.
28364669
2017
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
Biomarker
CTD_human
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
CausalMutation
CLINVAR
Ovarian cancer risk in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations.
12473589
2002
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
GeneticVariation
CLINVAR
Hereditary breast cancer in Middle Eastern and North African (MENA) populations: identification of novel, recurrent and founder BRCA1 mutations in the Tunisian population.
21603858
2012
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
GeneticVariation
CLINVAR
Missense mutations of BRCA1 gene affect the binding with p53 both in vitro and in vivo.
16969499
2006
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
GeneticVariation
CLINVAR
Novel BRCA1 and BRCA2 germline mutations and assessment of mutation spectrum and prevalence in Italian breast and/or ovarian cancer families.
16847550
2006
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
CausalMutation
CLINVAR
Genetic diagnosis of familial breast cancer using clonal sequencing.
20127978
2010
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
CausalMutation
CLINVAR
The role of targeted BRCA1/BRCA2 mutation analysis in hereditary breast/ovarian cancer families of Portuguese ancestry.
24916970
2015
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
CausalMutation
CLINVAR
Haplotype and quantitative transcript analyses of Portuguese breast/ovarian cancer families with the BRCA1 R71G founder mutation of Galician origin.
19123044
2009
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.700
GeneticVariation
CLINVAR
A high-throughput functional complementation assay for classification of BRCA1 missense variants.
23867111
2013